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[54,55] GLP-1 is said to exert neuroprotective, cardioprotective, nephroprotective, and immunomodulatory effects by acting through GLP-1 receptors located on many vital organs

As an essential intracellular antioxidant, reduced glutathione (-L-glutamyl-L cysteinylglycine, GSH) synthesis requires the cystine/glutamate antiporter system (encoded by SLC7A11 ) to import cystine from the environment and reduce it to cysteine

Studies have demonstrated that acute TRP depletion is associated with the emergence of depressive symptoms, potentially attributed to a significant reduction in 5-HT production (Chen et al., 2022)

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